
Opdivo Cost per Month: Nivolumab Price & Insurance Coverage in the USA (2025)
Opdivo (nivolumab) is one of the most widely used immunotherapy drugs in the United States, but its cost can be overwhelming for many cancer patients. In 2025, the monthly price of Opdivo ranges from $15,000 to over $20,000 before insurance, depending on dosage and treatment schedule. The good news is that Medicare, private insurance, and financial assistance programs can reduce these expenses significantly, sometimes lowering patient out-of-pocket costs to only a few hundred dollars per month. This guide explains the real cost of Opdivo per month, how insurance coverage works, and what assistance options are available to help patients manage treatment expenses.
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