Zepbound Cost in the US 2026: Monthly Price, Insurance Coverage, and Cheapest Pharmacy Deals
Zepbound Cost in the US 2026: Monthly Price, Insurance Coverage, and Cheapest Pharmacy Deals Zepbound (tirzepatide), Eli Lilly’s latest FDA-approved weight loss injection, continues to dominate the GLP-1 market in 2026. Closely related to Mounjaro, Zepbound helps control appetite and metabolism to support long-term weight loss. With the surge in demand, U.S. consumers are eager to know the updated 2026 Zepbound prices — both with and without insurance — along with the most affordable pharmacy options and savings programs. The average Zepbound list price in 2026 remains around $1,086/month before insurance or discounts. However, with Eli Lilly’s Self-Pay Program, eligible users can start from $349/month for 2.5 mg doses or $499 flat for higher doses (5–15 mg). Some private insurance plans lower costs to as little as $25 per month using official savings cards. Compared to similar GLP-1 drugs like Wegovy and Mounjaro, Zepbound stands out for its more aggressive pricing structure and broader availability across U.S. pharmacies and telehealth platforms.
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