2026 Drug Cost Guide: Keytruda, Wegovy, Mounjaro, Zepbound, Opdivo & Imfinzi Prices

Updated U.S. drug cost data (Keytruda, Wegovy, Mounjaro, Zepbound) — Insurance, savings & 2026 trends.

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Keytruda Cost in 2026: What You’ll Actually Pay (Latest U.S. Data & Savings Tips) - 2026 Drug Cost Analysis

Keytruda Cost in 2026: What You’ll Actually Pay (Latest U.S. Data & Savings Tips)

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In 2026, the real cost of Keytruda (pembrolizumab) continues to rise across the U.S., with list prices now reaching $11,564 per 200 mg dose or $23,590 for the 400 mg / 6-week schedule. While insurance coverage, assistance programs, and Medicare options can significantly reduce out-of-pocket costs, many American patients still face bills ranging from $1,200 to $10,000 per month, depending on their plan. This article breaks down updated Keytruda pricing data for 2026, compares infusion costs by hospital and pharmacy, explains copay assistance options, and provides the latest policy updates about potential government price negotiations. You’ll also find detailed FAQs addressing what patients in the U.S. are actually paying, how insurance affects coverage, and where to find verified cost-saving programs. Read on to discover the latest Keytruda prices, insurance breakdowns, and patient support options available in 2026.

Imfinzi Cost in the USA 2025: Price, Treatment for Lung Cancer, and Insurance Coverage - 2026 Drug Cost Analysis

Imfinzi Cost in the USA 2025: Price, Treatment for Lung Cancer, and Insurance Coverage

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Imfinzi Cost in the USA 2025: What Patients Need to Know Imfinzi (durvalumab) has become a vital immunotherapy option for patients with lung cancer in the United States, but its price remains a major concern in 2025. The average cost of a single Imfinzi infusion is estimated at $10,000–$12,000, which means that annual treatment expenses can easily exceed $140,000 per year before insurance or assistance programs are applied. For patients and caregivers, understanding the true cost of Imfinzi involves more than just the drug’s wholesale price. Factors such as insurance coverage, Medicare Part B rules, infusion center administration fees, and manufacturer co-pay assistance all play a role in determining what you will actually pay out-of-pocket. The good news is that programs like AstraZeneca Access 360 and patient savings support can dramatically lower costs, sometimes reducing co-pays to as little as $0 for eligible patients. In this updated 2025 guide, we provide detailed price breakdowns, comparisons with other immunotherapies like Keytruda and Opdivo, insurance coverage insights, and 20 frequently asked questions (FAQs) to help you navigate Imfinzi’s financial impact.

Keytruda Price Per Dose vs. Per Year — Full Breakdown (2025) - 2026 Drug Cost Analysis

Keytruda Price Per Dose vs. Per Year — Full Breakdown (2025)

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Keytruda (pembrolizumab) is one of the most widely prescribed immunotherapy drugs for cancer, but its cost continues to be a major concern for patients in 2025. On average, a single 200 mg intravenous dose is estimated at around $11,700 under Medicare ASP pricing, while a 6-week 400 mg dose carries a published list price of $23,590. Depending on the treatment plan, annual costs can exceed $200,000 per patient. In 2025, Merck also introduced a new subcutaneous formulation (Keytruda QLEX), which offers shorter administration times but could bring different pricing models compared to IV dosing. Insurance coverage, Medicare billing rules, and patient assistance programs remain critical factors in determining real out-of-pocket costs.

Drug Price FAQs: Keytruda, Wegovy, Mounjaro & More

The average cost of Keytruda without insurance in 2026 is around $10,000 to $13,000 per dose. With insurance, out-of-pocket expenses can be as low as $100 depending on the coverage.

Experts expect Zepbound’s price to drop by 10–15% in 2026 as competition and insurance coverage expand. Savings cards and manufacturer programs are also expected to continue.

Wegovy costs between $25 and $150 per month with most insurance plans in the U.S. Without insurance, the price is around $1,350 monthly.

Top Drug Comparisons 2026: Keytruda, Mounjaro, Wegovy & Zepbound

Keytruda vs Opdivo

Compare the 2026 cost, effectiveness, and insurance coverage of both cancer treatments.

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Wegovy vs Zepbound

Find out which weight-loss drug offers the best value and results in 2026.

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Mounjaro Savings 2026

Learn how to get the best savings and discounts for Mounjaro through insurance and cards.

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2026 UPDATE
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2026 Drug Cost Guide
Keytruda • Wegovy • Mounjaro • Zepbound
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Trending Drug Prices 2026
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Keytruda
$12,500/month
+5.2%
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Wegovy
$1,349/month
-2.1%
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Mounjaro
$1,023/month
+3.8%
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Zepbound
$1,059/month
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Keytruda Cost in the USA: How Much Does Pembrolizumab Really Cost in 2025?
Keytruda Cost in the USA: How Much Does Pembrolizumab Really Cost in 2025?
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How Much Does Keytruda Cost Per Month?
How Much Does Keytruda Cost Per Month?
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Keytruda Price Per Dose vs. Per Year — Full Breakdown (2025)
Keytruda Price Per Dose vs. Per Year — Full Breakdown (2025)
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