2026 Drug Cost Guide: Keytruda, Wegovy, Mounjaro, Zepbound, Opdivo & Imfinzi Prices

Updated U.S. drug cost data (Keytruda, Wegovy, Mounjaro, Zepbound) — Insurance, savings & 2026 trends.

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Tirzepatide Cost in the US 2026: Monthly Price, Insurance Coverage, and Cheapest Pharmacy Options - 2026 Drug Cost Analysis

Tirzepatide Cost in the US 2026: Monthly Price, Insurance Coverage, and Cheapest Pharmacy Options

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In 2026, Tirzepatide (brand name Zepbound) remains one of the most in-demand GLP-1 medications in the U.S. for weight loss and diabetes management. This article explores the latest updates on Tirzepatide’s monthly cost, insurance coverage changes for 2026, state-by-state Medicaid rules, and the cheapest pharmacy deals at Walmart, CVS, and GoodRx. We also compare Tirzepatide vs. Semaglutide to help you decide which GLP-1 treatment is best for your health and budget.

Drug Price FAQs: Keytruda, Wegovy, Mounjaro & More

The average cost of Keytruda without insurance in 2026 is around $10,000 to $13,000 per dose. With insurance, out-of-pocket expenses can be as low as $100 depending on the coverage.

Experts expect Zepbound’s price to drop by 10–15% in 2026 as competition and insurance coverage expand. Savings cards and manufacturer programs are also expected to continue.

Wegovy costs between $25 and $150 per month with most insurance plans in the U.S. Without insurance, the price is around $1,350 monthly.

Top Drug Comparisons 2026: Keytruda, Mounjaro, Wegovy & Zepbound

Keytruda vs Opdivo

Compare the 2026 cost, effectiveness, and insurance coverage of both cancer treatments.

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Wegovy vs Zepbound

Find out which weight-loss drug offers the best value and results in 2026.

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Mounjaro Savings 2026

Learn how to get the best savings and discounts for Mounjaro through insurance and cards.

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2026 UPDATE
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2026 Drug Cost Guide
Keytruda • Wegovy • Mounjaro • Zepbound
Insurance Coverage Savings Tips Price Trends
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Average Savings: 65%
Trending Drug Prices 2026
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Keytruda
$12,500/month
+5.2%
⚖️
Wegovy
$1,349/month
-2.1%
📊
Mounjaro
$1,023/month
+3.8%
💉
Zepbound
$1,059/month
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