How Much Does Opdivo Cost in the USA? | Nivolumab Price 2025

Opdivo (generic name: nivolumab) is one of the leading immunotherapy drugs in the class of PD-1 checkpoint inhibitors. It is approved for several cancers, including melanoma, non-small cell lung cancer, kidney cancer, liver cancer, and certain colorectal cancers.

But one of the most pressing questions for patients and families is: How much does Opdivo cost in the United States in 2025?

Below, you’ll find updated price information, factors that affect patient costs, financial assistance programs, and answers to the most frequently asked questions.

Updated Opdivo Prices in the USA (2025)

💡 Note: These are list prices (before insurance or discounts). The actual out-of-pocket cost varies widely depending on insurance coverage and assistance programs.

Factors That Influence Patient Cost

1. Insurance coverage

   • Commercial insurance may cover most or all of the cost.

   • Medicare Part B covers Opdivo when administered in a clinic or hospital setting.

   • Medicaid may cover it fully in certain states.

2. Dosage and treatment frequency

   • Treatment may be every 2 weeks, 3 weeks, or 4 weeks depending on the cancer type and stage.

3. Treatment combination

   • Opdivo is often used with Yervoy (ipilimumab) or chemotherapy, which increases overall costs.

4. Location and healthcare facility fees

   • Hospital vs outpatient clinic billing can lead to major cost differences.

5. New administration options

   • The new subcutaneous injection (Opdivo Qvantig) may reduce infusion-related costs.

Financial Assistance Programs

• BMS Access Support – Opdivo Access: helps patients navigate insurance, co-pay assistance, or free drug programs.

• BMS Co-Pay Assistance – eligible commercially insured patients may pay as little as $0 per treatment.

• BMS Patient Assistance Foundation – free medication for uninsured or low-income patients (BMS Foundation).

• GoodRx & Drugs.com – compare local pharmacy costs, discounts, and coupons (GoodRx Opdivo).

Latest 2025 Update

• FDA approval (Dec 2024) of Opdivo Qvantig, a subcutaneous injection version, makes administration faster and potentially more convenient than IV infusion.

• This may improve patient experience and reduce costs related to clinic time, though the drug’s base price remains similar.

Top 10 FAQs about Opdivo Cost

1. How much does Opdivo cost per month in the USA?
   → On average, between $7,000–$15,000 per month, depending on dosage and frequency.

2. Does insurance cover Opdivo?
   → Most U.S. commercial plans and Medicare Part B provide coverage, though co-pays vary.

3. Can I get Opdivo for free?
   → Yes, through the BMS Patient Assistance Foundation if you qualify.

4. Is Opdivo cheaper in other countries?
   → Yes. Prices are significantly lower in Europe, Canada, and some Asian countries due to government price controls.

5. What is the new Opdivo Qvantig?
   → A subcutaneous injection version of nivolumab, FDA-approved in Dec 2024.

6. How long do patients usually stay on Opdivo?
   → It depends on cancer type and response. Some patients continue for 1–2 years.

7. Does Medicare Part D cover Opdivo?
   → No. Since it’s given in a clinical setting, it falls under Medicare Part B.

8. Can I use discount programs like GoodRx for Opdivo?
   → Yes, but savings are usually limited since Opdivo is often billed through infusion centers, not retail pharmacies.

9. What if I don’t have insurance?
   → You can apply for BMS Patient Assistance for free or reduced-cost drug supply.

10. Are there WhatsApp numbers for support?
    → Official programs do not list WhatsApp, but patients can contact BMS directly at 1-800-861-0048 or through their support website. Some cancer support communities also use WhatsApp for patient networking.

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