2026 Drug Cost Guide: Keytruda, Wegovy, Mounjaro, Zepbound, Opdivo & Imfinzi Prices

Updated U.S. drug cost data (Keytruda, Wegovy, Mounjaro, Zepbound) — Insurance, savings & 2026 trends.

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How Much Does Keytruda Cost in the US in 2025? - 2026 Drug Cost Analysis

How Much Does Keytruda Cost in the US in 2025?

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How Much Does Keytruda Cost in the US in 2025? Price per Dose, Monthly Cost, and Insurance Coverage Updated: October 1, 2025 Keytruda (pembrolizumab) remains one of the most prescribed immunotherapy treatments for cancers such as melanoma, non-small cell lung cancer, and head and neck cancers. But for patients and families, the most pressing question is often: “How much does Keytruda cost in the US in 2025?” In this guide, we break down the latest Keytruda prices per dose, monthly treatment costs, and annual expenses. We also compare prices from leading sources like GoodRx , Drugs.com , and SingleCare to help you understand the current landscape. Beyond raw prices, we explain how insurance coverage, Medicare, and manufacturer assistance programs can dramatically reduce out-of-pocket costs. If you or a loved one are exploring treatment with Keytruda, this resource provides the most up-to-date 2025 information to help you plan financially and discuss options with your healthcare provider.

Imfinzi Cost in the USA 2025: Price, Treatment for Lung Cancer, and Insurance Coverage - 2026 Drug Cost Analysis

Imfinzi Cost in the USA 2025: Price, Treatment for Lung Cancer, and Insurance Coverage

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Imfinzi Cost in the USA 2025: What Patients Need to Know Imfinzi (durvalumab) has become a vital immunotherapy option for patients with lung cancer in the United States, but its price remains a major concern in 2025. The average cost of a single Imfinzi infusion is estimated at $10,000–$12,000, which means that annual treatment expenses can easily exceed $140,000 per year before insurance or assistance programs are applied. For patients and caregivers, understanding the true cost of Imfinzi involves more than just the drug’s wholesale price. Factors such as insurance coverage, Medicare Part B rules, infusion center administration fees, and manufacturer co-pay assistance all play a role in determining what you will actually pay out-of-pocket. The good news is that programs like AstraZeneca Access 360 and patient savings support can dramatically lower costs, sometimes reducing co-pays to as little as $0 for eligible patients. In this updated 2025 guide, we provide detailed price breakdowns, comparisons with other immunotherapies like Keytruda and Opdivo, insurance coverage insights, and 20 frequently asked questions (FAQs) to help you navigate Imfinzi’s financial impact.

Best Cardiac Surgeons in USA 2025: Costs, Success Rates, and How to Choose - 2026 Drug Cost Analysis

Best Cardiac Surgeons in USA 2025: Costs, Success Rates, and How to Choose

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In 2025, the United States remains a global leader in advanced heart care, offering world-class cardiac surgeons, innovative procedures, and some of the highest survival rates worldwide. But for patients, navigating the real costs of heart surgery, understanding success rates, and choosing the right surgeon can feel overwhelming. This guide breaks down what you need to know — from average 2025 prices for bypass and valve surgery, to how leading hospitals like Cleveland Clinic and Mayo Clinic compare, and the exact questions to ask before trusting your heart to a surgeon. Whether you’re considering open-heart surgery or newer minimally invasive techniques, this article provides the data, hospital links, and patient-friendly advice to make an informed decision.

How Much Does Semaglutide Cost in the US Without Insurance (2025) - 2026 Drug Cost Analysis

How Much Does Semaglutide Cost in the US Without Insurance (2025)

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In 2025, the cost of semaglutide (Ozempic, Wegovy, Rybelsus) in the United States remains one of the biggest challenges for patients without insurance. On average, the monthly out-of-pocket price ranges between $1,000 and $1,400, depending on dosage and brand. Even though semaglutide is highly effective for type 2 diabetes and weight loss, its high retail cost makes it inaccessible for many people. However, patients can lower their expenses through manufacturer savings programs, GoodRx coupons, and pharmacy discount cards, which may reduce the Wegovy cash price or Ozempic monthly cost to as little as $499. Alternatives such as Mounjaro (tirzepatide) or compounded semaglutide also exist, but safety and availability should always be considered. This guide explores real patient costs, discount programs, insurance coverage updates, and the future of GLP-1 drug pricing, helping you understand exactly what to expect if you’re paying for semaglutide out of pocket in 2025.

Top 10 Most Expensive Cancer Drugs in the U.S. (2025 Update) - 2026 Drug Cost Analysis

Top 10 Most Expensive Cancer Drugs in the U.S. (2025 Update)

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In 2025, cancer treatment costs in the United States remain among the highest in the world, with several oncology drugs carrying annual price tags well over $150,000. This article breaks down the Top 10 most expensive cancer drugs in the U.S., comparing per-dose and per-year costs, highlighting manufacturers, and explaining what patients actually pay after insurance. From blockbuster immunotherapies like Keytruda and Imfinzi to groundbreaking CAR-T and gene therapies priced at nearly half a million dollars per treatment, this guide provides a clear look at the latest pricing landscape and practical insights for patients navigating financial support programs.

Keytruda Price Per Dose vs. Per Year — Full Breakdown (2025) - 2026 Drug Cost Analysis

Keytruda Price Per Dose vs. Per Year — Full Breakdown (2025)

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Keytruda (pembrolizumab) is one of the most widely prescribed immunotherapy drugs for cancer, but its cost continues to be a major concern for patients in 2025. On average, a single 200 mg intravenous dose is estimated at around $11,700 under Medicare ASP pricing, while a 6-week 400 mg dose carries a published list price of $23,590. Depending on the treatment plan, annual costs can exceed $200,000 per patient. In 2025, Merck also introduced a new subcutaneous formulation (Keytruda QLEX), which offers shorter administration times but could bring different pricing models compared to IV dosing. Insurance coverage, Medicare billing rules, and patient assistance programs remain critical factors in determining real out-of-pocket costs.

Drug Price FAQs: Keytruda, Wegovy, Mounjaro & More

The average cost of Keytruda without insurance in 2026 is around $10,000 to $13,000 per dose. With insurance, out-of-pocket expenses can be as low as $100 depending on the coverage.

Experts expect Zepbound’s price to drop by 10–15% in 2026 as competition and insurance coverage expand. Savings cards and manufacturer programs are also expected to continue.

Wegovy costs between $25 and $150 per month with most insurance plans in the U.S. Without insurance, the price is around $1,350 monthly.

Top Drug Comparisons 2026: Keytruda, Mounjaro, Wegovy & Zepbound

Keytruda vs Opdivo

Compare the 2026 cost, effectiveness, and insurance coverage of both cancer treatments.

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Wegovy vs Zepbound

Find out which weight-loss drug offers the best value and results in 2026.

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Mounjaro Savings 2026

Learn how to get the best savings and discounts for Mounjaro through insurance and cards.

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2026 UPDATE
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2026 Drug Cost Guide
Keytruda • Wegovy • Mounjaro • Zepbound
Insurance Coverage Savings Tips Price Trends
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Average Savings: 65%
Trending Drug Prices 2026
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Keytruda
$12,500/month
+5.2%
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Wegovy
$1,349/month
-2.1%
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Mounjaro
$1,023/month
+3.8%
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Zepbound
$1,059/month
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All Articles 17 Advanced Cancer Stage Treatment Cost Breakdown 8 Cancer Treatment & Specialized Care 11 Cancer Treatment Cost & Financial Assistance 12 Cardiology & Heart Surgery 1 Dental Treatments 0 Dermatology & Skin Treatments 0 Eye Surgery 0 Fertility & IVF 0 Hair Transplant 3 Health Insurance Premiums & Oncology Coverage 13 Immunotherapy & Personalized Cancer Therapy Pricing 10 Oncology Drug Costs & Insurance 22 Orthopedic Surgery 0 Plastic & Cosmetic Surgery 0 Weight Loss Drug Costs & Insurance Coverage 5 Weight Loss Surgery 4
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Keytruda Cost in the USA: How Much Does Pembrolizumab Really Cost in 2025?
Keytruda Cost in the USA: How Much Does Pembrolizumab Really Cost in 2025?
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Keytruda Price Per Dose vs. Per Year — Full Breakdown (2025)
Keytruda Price Per Dose vs. Per Year — Full Breakdown (2025)
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Top 10 Most Expensive Cancer Drugs in the U.S. (2025 Update)
Top 10 Most Expensive Cancer Drugs in the U.S. (2025 Update)
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