2026 Drug Cost Guide: Keytruda, Wegovy, Mounjaro, Zepbound, Opdivo & Imfinzi Prices

Updated U.S. drug cost data (Keytruda, Wegovy, Mounjaro, Zepbound) — Insurance, savings & 2026 trends.

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Keytruda Cost in 2025: Real Monthly Price, Insurance Coverage & Patient Tips - 2026 Drug Cost Analysis

Keytruda Cost in 2025: Real Monthly Price, Insurance Coverage & Patient Tips

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Keytruda (pembrolizumab) is one of the most widely prescribed immunotherapy drugs for cancer — but its high cost often leaves patients wondering how much they will actually pay. In 2025, the average list price for a single Keytruda infusion is around $11,000–$12,000, with annual costs exceeding $190,000 before insurance. Fortunately, Medicare, Medicaid, and private insurers cover most of these expenses, and copay assistance programs can reduce patient costs to as little as $25 per infusion. This guide explains the real monthly price of Keytruda in 2025, how insurance coverage works, and practical tips patients can use to lower out-of-pocket expenses.

Opdivo Cost per Month: Nivolumab Price & Insurance Coverage in the USA (2025) - 2026 Drug Cost Analysis

Opdivo Cost per Month: Nivolumab Price & Insurance Coverage in the USA (2025)

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Opdivo (nivolumab) is one of the most widely used immunotherapy drugs in the United States, but its cost can be overwhelming for many cancer patients. In 2025, the monthly price of Opdivo ranges from $15,000 to over $20,000 before insurance, depending on dosage and treatment schedule. The good news is that Medicare, private insurance, and financial assistance programs can reduce these expenses significantly, sometimes lowering patient out-of-pocket costs to only a few hundred dollars per month. This guide explains the real cost of Opdivo per month, how insurance coverage works, and what assistance options are available to help patients manage treatment expenses.

How Much Does Keytruda Cost Per Month? - 2026 Drug Cost Analysis

How Much Does Keytruda Cost Per Month?

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Keytruda (pembrolizumab) has transformed cancer treatment, but its price tag remains one of the highest in oncology. In 2025, the average monthly cost of Keytruda in the United States is estimated at $15,000 to $16,000, depending on the dosing schedule. While list prices are staggering, most patients do not pay this full amount thanks to insurance coverage, Medicare benefits, and financial assistance programs. Still, questions like “How much does Keytruda cost per month?” and “Why is Keytruda so expensive?” are critical for patients, caregivers, and policymakers navigating the realities of modern cancer care.

Keytruda Price Per Infusion in USA | Updated 2025 Guide - 2026 Drug Cost Analysis

Keytruda Price Per Infusion in USA | Updated 2025 Guide

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If you or a loved one is considering immunotherapy, understanding the real cost of treatment is crucial. In 2025, the price of Keytruda (pembrolizumab) per infusion in the USA remains a major factor for patients, caregivers, and healthcare providers. On average, a single infusion can cost between $9,800 and $11,500, depending on insurance coverage, treatment duration, and hospital charges. This updated guide explores the latest Keytruda prices, available financial assistance programs, and key insurance considerations to help you plan more effectively. You’ll also find official resources, FAQs, and expert insights, making this one of the most comprehensive guides to Keytruda treatment costs in the USA today.

Keytruda Cost in the USA: How Much Does Pembrolizumab Really Cost in 2025? - 2026 Drug Cost Analysis

Keytruda Cost in the USA: How Much Does Pembrolizumab Really Cost in 2025?

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Keytruda (pembrolizumab) is one of the most widely used immunotherapy drugs for treating different types of cancer, including lung cancer, melanoma, and head and neck cancers. In the United States, the cost of Keytruda can be a major concern for patients and their families, as it is often priced at several thousand dollars per infusion. This article explores the average cost of Keytruda in the USA, insurance coverage options, financial assistance programs, and helpful resources for patients seeking more affordable access.

Drug Price FAQs: Keytruda, Wegovy, Mounjaro & More

The average cost of Keytruda without insurance in 2026 is around $10,000 to $13,000 per dose. With insurance, out-of-pocket expenses can be as low as $100 depending on the coverage.

Experts expect Zepbound’s price to drop by 10–15% in 2026 as competition and insurance coverage expand. Savings cards and manufacturer programs are also expected to continue.

Wegovy costs between $25 and $150 per month with most insurance plans in the U.S. Without insurance, the price is around $1,350 monthly.

Top Drug Comparisons 2026: Keytruda, Mounjaro, Wegovy & Zepbound

Keytruda vs Opdivo

Compare the 2026 cost, effectiveness, and insurance coverage of both cancer treatments.

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Wegovy vs Zepbound

Find out which weight-loss drug offers the best value and results in 2026.

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Mounjaro Savings 2026

Learn how to get the best savings and discounts for Mounjaro through insurance and cards.

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2026 UPDATE
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2026 Drug Cost Guide
Keytruda • Wegovy • Mounjaro • Zepbound
Insurance Coverage Savings Tips Price Trends
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Average Savings: 65%
Trending Drug Prices 2026
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Keytruda
$12,500/month
+5.2%
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Wegovy
$1,349/month
-2.1%
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Mounjaro
$1,023/month
+3.8%
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Zepbound
$1,059/month
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All Articles 17 Advanced Cancer Stage Treatment Cost Breakdown 8 Cancer Treatment & Specialized Care 11 Cancer Treatment Cost & Financial Assistance 12 Cardiology & Heart Surgery 1 Dental Treatments 0 Dermatology & Skin Treatments 0 Eye Surgery 0 Fertility & IVF 0 Hair Transplant 3 Health Insurance Premiums & Oncology Coverage 13 Immunotherapy & Personalized Cancer Therapy Pricing 10 Oncology Drug Costs & Insurance 22 Orthopedic Surgery 0 Plastic & Cosmetic Surgery 0 Weight Loss Drug Costs & Insurance Coverage 5 Weight Loss Surgery 4
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Keytruda Cost in the USA: How Much Does Pembrolizumab Really Cost in 2025?
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