
Top 10 Most Expensive Cancer Drugs in the U.S. (2025 Update)
In 2025, cancer treatment costs in the United States remain among the highest in the world, with several oncology drugs carrying annual price tags well over $150,000. This article breaks down the Top 10 most expensive cancer drugs in the U.S., comparing per-dose and per-year costs, highlighting manufacturers, and explaining what patients actually pay after insurance. From blockbuster immunotherapies like Keytruda and Imfinzi to groundbreaking CAR-T and gene therapies priced at nearly half a million dollars per treatment, this guide provides a clear look at the latest pricing landscape and practical insights for patients navigating financial support programs.
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