2026 Drug Cost Guide: Keytruda, Wegovy, Mounjaro, Zepbound, Opdivo & Imfinzi Prices

Updated U.S. drug cost data (Keytruda, Wegovy, Mounjaro, Zepbound) — Insurance, savings & 2026 trends.

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How Much Does Keytruda Cost with Insurance in the U.S.? - 2026 Drug Cost Analysis

How Much Does Keytruda Cost with Insurance in the U.S.?

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In 2026, most patients pay between $300 and $3,000 per month depending on their plan, deductible, and location. This complete guide breaks down Keytruda prices with and without insurance, Medicare coverage, patient assistance programs, and expert insights to help Americans save on cancer treatment costs.

Top 10 Most Expensive Cancer Drugs in the U.S. (2025 Update) - 2026 Drug Cost Analysis

Top 10 Most Expensive Cancer Drugs in the U.S. (2025 Update)

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In 2025, cancer treatment costs in the United States remain among the highest in the world, with several oncology drugs carrying annual price tags well over $150,000. This article breaks down the Top 10 most expensive cancer drugs in the U.S., comparing per-dose and per-year costs, highlighting manufacturers, and explaining what patients actually pay after insurance. From blockbuster immunotherapies like Keytruda and Imfinzi to groundbreaking CAR-T and gene therapies priced at nearly half a million dollars per treatment, this guide provides a clear look at the latest pricing landscape and practical insights for patients navigating financial support programs.

Drug Price FAQs: Keytruda, Wegovy, Mounjaro & More

The average cost of Keytruda without insurance in 2026 is around $10,000 to $13,000 per dose. With insurance, out-of-pocket expenses can be as low as $100 depending on the coverage.

Experts expect Zepbound’s price to drop by 10–15% in 2026 as competition and insurance coverage expand. Savings cards and manufacturer programs are also expected to continue.

Wegovy costs between $25 and $150 per month with most insurance plans in the U.S. Without insurance, the price is around $1,350 monthly.

Top Drug Comparisons 2026: Keytruda, Mounjaro, Wegovy & Zepbound

Keytruda vs Opdivo

Compare the 2026 cost, effectiveness, and insurance coverage of both cancer treatments.

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Wegovy vs Zepbound

Find out which weight-loss drug offers the best value and results in 2026.

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Mounjaro Savings 2026

Learn how to get the best savings and discounts for Mounjaro through insurance and cards.

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2026 UPDATE
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2026 Drug Cost Guide
Keytruda • Wegovy • Mounjaro • Zepbound
Insurance Coverage Savings Tips Price Trends
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Average Savings: 65%
Trending Drug Prices 2026
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Keytruda
$12,500/month
+5.2%
⚖️
Wegovy
$1,349/month
-2.1%
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Mounjaro
$1,023/month
+3.8%
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Zepbound
$1,059/month
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All Articles 2 Advanced Cancer Stage Treatment Cost Breakdown 8 Cancer Treatment & Specialized Care 11 Cancer Treatment Cost & Financial Assistance 9 Cardiology & Heart Surgery 1 Dental Treatments 0 Dermatology & Skin Treatments 0 Eye Surgery 0 Fertility & IVF 0 Hair Transplant 3 Health Insurance Premiums & Oncology Coverage 11 Immunotherapy & Personalized Cancer Therapy Pricing 6 Oncology Drug Costs & Insurance 18 Orthopedic Surgery 0 Plastic & Cosmetic Surgery 0 Weight Loss Drug Costs & Insurance Coverage 5 Weight Loss Surgery 4
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